Mechanical anisotropy probed by single molecule atomic force microscopy: from proteins to molecular clusters to materials
发布时间: 2018-10-15     浏览次数: 17



时间:2018-10-15  10:00





Curriculum Vitae
Department of Chemistry
University of British Columbia
Vancouver, BC, V6T 1Z1
Tel: 604-822-9669
Fax: 604-822-2847


09/1993-12/1998 Ph. D., Polymer Chemistry and Physics, Jilin University, P. R. China
09/1996 –09/1997 Joint training Ph.D. student, University of Munich, Germany
09/1989-07/1993 B. S., Polymer Engineering; Minor: Technical Economy and Management, Tianjin University, P. R. China

Professional Experience
07/2013-present Professor, Department of Chemistry, University of British Columbia, Canada
10/2004-09/2014 Canada Research Chair (Tier II) in Molecular Nanoscience and Protein Engineering,
Department of Chemistry, University of British Columbia, Canada
07/2009-06/2013 Associate Professor with tenure, Department of Chemistry, University of British
Columbia, Canada
08/2004-06/2009 Assistant Professor, Department of Chemistry, University of British Columbia,
08/2002-08/2004 Associate Research Scientist, Columbia University, New York, NY, USA.
01/1999-08/2002 Research Fellow, Mayo Medical Center, Rochester, MN, USA

Honors and Awards

2017 Plenary Speaker, the 15th Pacific Polymer Congress

2016 Applied Chemsitry Lectureship, Changchun Institute of Applied Chemistry
2012 Changjiang Scholar Distinguished Professor, Jilin University
2011 JILA Distinguished Visiting Fellowship
2011 Alexander von Humboldt Foundation Research Fellowship
2011 Charles A. McDowell Award for Excellence in Research
2010-2013 NSERC Discovery Accelerator Supplement Award
2006-2012 Career Investigator Award, Michael Smith Foundation for Health

2004-2014 Canada Research Chair (Tier II) in Molecular Nanoscience and Protein Engineering

Research Interests
Protein mechanics and engineering at the single molecule level, Protein-based biomaterials
Protein folding and unfolding dynamics

Selected Publications (since 2010)

1. Li, H. and Zheng, P. Curr. Opin Chem. Biol., 43, 58-67 (2018).
2. Lei, H., Guo, Y., Hu, X., Hu, C., Hu, X. and Li, H. B. J. Am. Chem. Soc. 139, 1358 (2017).
3. Lei, H., He, C., Hu, C., Li, J., Hu, X., Hu, X. and Li, H. Angew. Chem. Int. Ed., 56, 6117 (2017).
4. Lyu, S., Fang, J., Duan, T., Fu, L., Liu, J. and Li, H. Chem. Commun., 53, 13375 (2017).
5. Gao, X., Lyu, S. and Li, H. Biomacromolecules, 18, 3726-3732 (2017).
6. Gao, X., Fang, J., Xue, B., Fu, L. and Li, H. Biomacromolecules, 17, 2812−2819 (2016).
7. Zheng, P., Arantes, G. M., Field, M. J. and Li, H. B. Nature Commun., 6, 7569 (2015).
8. He, C., Hu, C., Hu, X., Hu, X., Xiao, A., Perkins, T.T. and Li, H. B. Angew. Chem. Intnl. Ed., 54, 9921 (2015).
9. Zheng, P., Wang, Y. and Li, H. Angew. Chem. Int. Ed. 53, 14060-14063 (2014).
10. Kong, N., Peng, Q. and Li, H., Adv. Funct. Mater. 24, 7310–7317 (2014).
11. He, C., Lamour, G., Xiao, A., Gsponer, J., Li, H. J. Am. Chem. Soc. 136, 11946−11955 (2014).
12. Fang, J., Mehlich, A., Koga, N., Huang, J., Koga, R., Gao, X., Hu, C., Jin, C., Rief, M., Kast, J., Baker, D., Li, H. Nature Commun., 4, 2974 (2013).
13. Zoldak, G. ; Stigler, J. ; Pelz, B. ; Li, H. ; Rief, M. Proc. Natl. Acad. Sci. USA., 110, 18156-18161 (2013).
14. Zheng, P., Takayama, S.J., Mauk, A.G. and Li, H. B. J. Am. Chem. Soc., 134, 4124-4131(2012).
15. Zheng, P. and Li, H., J. Am. Chem. Soc. 133, 6791-6798 (2011).
16. Aioanei, D., Lv, S., Tessari, I., Rampioni, A. Bubacco, L., Li, H. Samori, B. and Brucale, M., Angew. Chem. Int. Ed. Engl. 50, 4394-4397 (2011).
17. Lv, S., Dudek, D.M., Cao, Y., Balamurali, M.M., Gosline, J. & Li, H. Nature, 465, 69-73 (2010)
18. Li, H. and Cao, Y., Acc. Chem. Res. 43, 1331-1341 (2010).

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